Tissue Engineering Scaffolds: History, Types and Construction Methods
نویسندگان
چکیده مقاله:
Tissue engineering is a rapidly growing research field, potentially capable of de novo tissue and organ construction. This approach is used to improve efficiency both in the tissue and cell culture. This method is required to provide bodies in vivo three-dimensional conditions outside of the body (ex vivo). To achieve this goal, given tissue cells are cultured on the tissue engineering scaffolds. These are structures with on extracellular matrix materials on which different treatments are performed. Initially, they were only used to deliver drugs and hormones, but further investigations revealed their ability to preserve, protect and even transfer cells into the body. Now widespread employment of scaffolds for organ transplantation is in a rapid progress. To improve the organ transplantation materials and structures similar to the target tissues areused. Applying scaffolds for cell reproduction is an ongoing research aimed to increase the efficiency of three-dimensional culture. This goal necessitates the simulation of bodies internal environment which is provided by simultaneous culture of target cells with stromal cells. Present review is a comprehensive study of available information in connection with main aspects of scaffolding. It primarily includes their history, materials and types, scaffolding construction methods and their applications in medicine as well as tissue engineering.
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عنوان ژورنال
دوره 9 شماره None
صفحات 0- 0
تاریخ انتشار 2011-08
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